目的探討結(jié)直腸癌患者行腹腔鏡切除術(shù)后機(jī)體應(yīng)激反應(yīng)的變化。方法選擇同期腹腔鏡下和常規(guī)的結(jié)直腸癌切除術(shù)患者各30例進(jìn)行前瞻性研究,比較兩種術(shù)式術(shù)后的體溫、止痛劑用量、腸蠕動(dòng)恢復(fù)時(shí)間、C反應(yīng)蛋白、白細(xì)胞計(jì)數(shù)和白細(xì)胞介素6(IL6)的變化。結(jié)果結(jié)直腸癌腹腔鏡切除術(shù)組的術(shù)后體溫和白細(xì)胞計(jì)數(shù)的變化與常規(guī)開腹組相比無統(tǒng)計(jì)學(xué)差異,而止痛劑用量、腸蠕動(dòng)恢復(fù)時(shí)間、C反應(yīng)蛋白和術(shù)后第1天 IL6水平均明顯低于常規(guī)開腹組(P<0.01,P<0.05)。結(jié)論結(jié)直腸癌腹腔鏡切除術(shù)對(duì)機(jī)體應(yīng)激反應(yīng)的影響明顯輕于常規(guī)開腹組,恢復(fù)早于常規(guī)開腹組,顯示了微創(chuàng)的優(yōu)越性。
引用本文: 田文,李榮,陳凜. 結(jié)直腸癌腹腔鏡切除術(shù)對(duì)機(jī)體應(yīng)激反應(yīng)影響的臨床研究. 中國普外基礎(chǔ)與臨床雜志, 2004, 11(3): 204-208. doi: 復(fù)制
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1. | Jakeways MS, Mitchell V, Hashim IA, et al. Metabolic and inflammatory responses after open or laparoscopic cholecystectomy [J]. Br J Surg, 1994; 81(1)∶127. |
2. | Bellon JM, Manzano L, Bernardos L, et al. Cytokine levels after open and laparoscopic cholecystectomy [J]. Eur Surg Res, 1997; 29(1)∶27. |
3. | 田文,李榮,陳凜,等. 手助腹腔鏡的結(jié)直腸癌根治術(shù) [J]. 中華外科雜志, 2003; 41(1)∶70. |
4. | Kwok SP, Lau WY, Carey PD, et al. Prospective evaluation of laparoscopicassisted large bowel excision for cancer [J]. Ann Surg, 1996; 223(2)∶170. |
5. | 曾和平, 葉古祥, 潘芳芳, 等. 腹腔鏡膽囊切除術(shù)對(duì)機(jī)體應(yīng)激反應(yīng)的影響 [J]. 中國普通外科雜志, 2001; 10(1)∶35. |
6. | 朱江帆主編. 普通外科內(nèi)鏡手術(shù)學(xué) [M]. 濟(jì)南: 山東科學(xué)技術(shù)出版社, 2001∶69~71. |
- 1. Jakeways MS, Mitchell V, Hashim IA, et al. Metabolic and inflammatory responses after open or laparoscopic cholecystectomy [J]. Br J Surg, 1994; 81(1)∶127.
- 2. Bellon JM, Manzano L, Bernardos L, et al. Cytokine levels after open and laparoscopic cholecystectomy [J]. Eur Surg Res, 1997; 29(1)∶27.
- 3. 田文,李榮,陳凜,等. 手助腹腔鏡的結(jié)直腸癌根治術(shù) [J]. 中華外科雜志, 2003; 41(1)∶70.
- 4. Kwok SP, Lau WY, Carey PD, et al. Prospective evaluation of laparoscopicassisted large bowel excision for cancer [J]. Ann Surg, 1996; 223(2)∶170.
- 5. 曾和平, 葉古祥, 潘芳芳, 等. 腹腔鏡膽囊切除術(shù)對(duì)機(jī)體應(yīng)激反應(yīng)的影響 [J]. 中國普通外科雜志, 2001; 10(1)∶35.
- 6. 朱江帆主編. 普通外科內(nèi)鏡手術(shù)學(xué) [M]. 濟(jì)南: 山東科學(xué)技術(shù)出版社, 2001∶69~71.